
In studies and surveys conducted between 2017 and 2020 among 25, 594 men, 45% indicated that they would like to have a larger penis. However, few people decide to have surgery. Today there is an alternative to surgical intervention: penis enlargement with hyaluronic acid (HA-hyaluronic acid). In the article we will understand all aspects of this technique, its effectiveness and safety.
What is this procedure
Penis enlargement with hyaluronic acid is a minimally invasive procedure that involves introducing a biocompatible filler under the skin of the penis or glans using fine needles or Venfor (cannulas). The result after correction appears immediately and lasts from one to two years, depending on the characteristics of the filler itself.
Hyaluronate is a temporary filler and has been approved as a safe and effective soft tissue plumping agent. This way you can increase the penis circumference by 2-3 cm and its length by 1-3 cm. Moreover, during the first month the effect constantly increases. Indeed, hyaluronic acid attaches and retains water molecules, thus increasing the volume of the penis.
In aesthetic medicine, several names are used for this method of penis enlargement:
- plastic surgery of the intimate contour;
- penis enlargement with hyaluronate;
- intimate filling;
- injection phalloplasty.
Increasing penis size with hyaluronic acid is a non-surgical procedure, carried out on an outpatient basis, and the patient can go home immediately after administering the drug.

Increasing penis size with hyaluronic acid is a safe procedure. The need for safer, more effective and less invasive treatments has increased across all areas of modern medicine. Penis enlargement with hyaluronic acid solves three problems at once: medical, psychological and aesthetic. In the United States, soft tissue fillers are the second most popular minimally invasive procedure, with more than 2. 6 million fillers performed in 2019.
Is it necessary to enlarge the penis with fillers?
Each case is individual and it is impossible to give a universal answer. With a good erection, even a small penis can give pleasure to a woman and bring her to orgasm. This is because the most sensitive G-spot is located on the front wall, at the entrance to the vagina. You can learn more about normal penis size in this article.
Indications for injections into the shaft of the penis
The introduction of hyaluronate into the diaphysis of the genital organ is carried out for several indications:
- psychological problems associated with small penis size;
- insignificant thickness of the penis, or the so-called "thin penis";
- insufficient stimulation of the partner's vagina during sexual intercourse and her dissatisfaction;
- disproportion in the parameters of the genital organs of the partners (large vaginal volume and small penis);
- erectile dysfunction of a psychogenic nature associated with failure-expectation syndrome due to small penis size;
- Peyronie’s disease – curvature of the shaft of the penis;
- urethral defects;
- consequences of unsuccessful operations on the genital organ;
- fibrosis of the corpora cavernosa;
- genetic and hormonal pathologies leading to underdevelopment of the penis, micropenis.
It should be noted that the correction of hyaluronic acid in the penis shaft does not increase the length of the penis, but only gives it volume, increasing the size of the girth and diameter, although visually the penis appears moreimpressive in a calm state and during an erection.
Indications for injections into the head of the penis
Minimally invasive enlargement of the head of the penis with hyaluronic acid is carried out for the following indications:
- small size of the head of the penis in relation to the shaft (thin head);
- the top of the head is insufficiently pronounced;
- brake smoothed;
- wrinkled mucous membrane of the head;
- deformation of the head of the penis after injury;
- premature ejaculation.
This head correction can not only improve its shape, but also increase its length.
What results can we expect after the injections?
After introducing filler into the shaft, its circumference increases by 1-2 cm, and the intervention in the glans not only improves its aesthetic qualities, but also lengthens the penis by 3-5 cm. Once under the skin, hyaluronate is evenly distributed, smoothing the skin and mucous membranes, improving the appearance of the penis. The administration of the gel makes it possible to increase the relief of the corolla of the head, its width, to highlight the frenulum, to make it more convex, to modify the shape and volume of the head.
At rest, the hyaluronate-filled penis is heavier, so it appears longer, because it is not retracted into the groin. When erect, it appears thicker than before the injections, but the length remains the same.
Gel injections into the head of the penis help men suffering from premature ejaculation to cope with this problem. Hyaluronate is injected into the sensitive part of the head - the frenulum. The substance penetrates the subcutaneous layer and is distributed in the intercellular space, shifting certain receptors to the lower subcutaneous layers. As a result, the sensitivity of the penis decreases and the man can control the onset of orgasm.

How long does the effect last?
The results of the first filler injection last from nine months to two years. Additionally, the volume constantly increases during the first six months due to the fact that the disintegrated short hyaluronate units retain more water. The enzyme dehyaluronidase then gradually breaks down the acid. After 12 months, more than 30% of the gel disintegrates. To restore the volume, it is recommended to repeat the procedure. Hyaluronate tends to break down less with repeated injections.
According to reviews, such penis enlargement with hyaluronic acid increases the sexual attractiveness of a man, increases the quantity and quality of sexual intercourse, while experiencing more vivid sensations due to additional stimulation and givingpleasure to his partner, which also increases the man's self-esteem.
Is hyaluronic acid safe?
Hyaluronic acid (hyaluronate, hyaluronic acid) belongs to mucopolysaccharides and is part of the epithelium, nervous and connective tissues. It is contained in the extracellular space, in a biological fluid, in particular a biological lubricant. The body of a person of average weight contains about 16 g of this substance. Hyaluronate is involved in tissue hydrodynamics and cell reproduction. It is with this particularity that its regenerating effect is associated.
The substance contains up to 25, 000 disaccharide units and is capable of retaining the same amount of water. It is this ability of the polysaccharide that gives extra volume to the hyaluronate and penile tissues. Therefore, the introduction of exogenous hyaluronic acid is absolutely safe for humans.
This compound is not rejected by the body and does not cause allergies. It has been used in medicine since the 80s of the last century to increase the viscosity of synovial fluid in the joints. The technique of increasing the volume and length of the penis with hyaluronic gel appeared relatively recently, but has gained the trust of men as an effective procedure that does not require surgery.
Recommendations for choosing a hyaluronic acid filler
The choice of filler product is up to the doctor. The gels differ in their composition, density and percentage of hyaluronic acid. Some fillers add a local anesthetic to reduce pain after the procedure, but these formulations are more expensive. The density is chosen by the doctor depending on the objectives and the injection site.
Many injectable penile fillers state that the product contains cross-linked hyaluronic acid. It consists of alternating monomers of DN-acetylglucosamine and D-glucuronic acid. The monomer units are cross-linked into a polymer using biocompatible urea. Such cross-linked biopolymers tend to last longer in the implanted area than conventional hyaluronate and improve the filling quality of the penile tissue.
How to achieve penis enlargement with hyaluronic acid
The procedure itself is preceded by a preparatory stage. The andrologist collects anamnesis, asks about systemic and chronic diseases, psychological problems and conducts an examination. Patients consent to the processing of their personal data. Before the intervention, tests are carried out:
- general blood test;
- urine test;
- blood test for clotting.
Additional studies may be necessary as indicated.
Penis augmentation with hyaluronate is carried out on an outpatient basis. Before the correction, the groin hair is shaved. The procedure is performed under local anesthesia.
The introduction of the filler into the penis takes place in several stages:
- The groin area is treated with an antiseptic and covered with a sterile disposable diaper.
- An anesthetic gel is applied to the penis, which takes effect after 15 minutes.
- The required amount of medicine containing hyaluronic acid is drawn into the syringe. A thin needle is inserted into the subcutaneous layer and the filler is injected slowly. The doctor makes sure that the hyaluronate is evenly distributed in the injection area.
- An aseptic bandage and patch are applied to the injection site.
The duration of the procedure depends on the number of injections and lasts from half an hour to an hour, taking into account the anesthesia time at the sites of introduction of hyaluronic acid

Methods of administration
There are several methods for introducing filler into the head of the penis. The doctor chooses the technique based on the indications. Most often, several methods are combined to improve the aesthetics of the head of the penis:
- Fan method— hyaluronate is injected with a thin needle in different directions through a fan-shaped puncture.
- Point method- the injection is carried out on a limited part of the penis to eliminate irregularities or deformations.
- Introduction to contoursThe putty is applied along the crown of the head, after which the contour becomes voluminous and more pronounced.
Features of the recovery period
After correction, pain may occur at the injection sites, which can be easily relieved with lidocaine spray. The penis appears swollen and small bruises may appear. The swelling can persist for up to 5 days, the hematomas disappear on the 6th day. There is slight redness at the injection site. All these changes should not be scary. It must be taken into account that it is a very sensitive organ with a large number of nerve endings and small vessels. Many men report frequent nocturnal erections after the procedure. Serious complications are extremely rare and are most often associated with poor hygiene and infection of injection sites, which become entry points for microorganisms. Sometimes hyperpigmentation can be seen at the site of the hematoma.
Restrictions after the procedure
After the introduction of hyaluronic acid, there are a number of restrictions and recommendations:
- interrupt intimate life for two weeks;
- antibiotics are needed for 5 days, then as indicated;
- be sure to treat the penis with anti-inflammatory and antiseptic agents;
- do not take hot baths, exclude baths and saunas for a week.
Contraindications
Like any other procedure, filler injection has a number of contraindications:
- exacerbation of chronic diseases;
- blood diseases, including bleeding disorders;
- inflammatory diseases and acute viral infections (fever, fever);
- take antibiotics and blood thinners;
- immune system diseases;
- herpes in the acute stage;
- malignant tumors;
- diabetes.
Hyaluronate injections are not performed if a man at this time has a high body temperature, fever or if he has rashes or ulcerations on the penis.
Clinical studies of the results of filler injections
Fillers appeared in our country relatively recently, therefore no long-term clinical studies in this area have been conducted. However, such experience has been accumulated in foreign clinics. The results of one of the long-term observations carried out in the urology department of Cha Meditech Co. , Ltd. clinic. , in Korea, by scientists led by Professor De Yul Yang have already been published. These studies aimed to summarize the long-term clinical outcomes of hyaluronic acid (HA) injections.
The multicenter randomized trial was conducted for 18 months after a single injection of filler between November 2016 and May 2018. It included 67 healthy men aged 20 to 66 who considered their penises smaller than normal foran adult.
All observed men underwent an initial examination before the study and a detailed medical history was compiled, with emphasis on psychiatric and psychological problems. They have consented to the processing of their personal information.
The study was conducted using SAS version 9. 4 (SAS Institute Inc. , Cary, NC, USA) by an independent biostatistician. During the blinded portion of the study, all postinjection assessments at each site were performed by an independent physician who was not involved in screening or injection of the excipients.
search results
Overall, the penises were smooth, natural and supple, and the increase in girth was maintained for up to a year and a half after the filler injections. No irregularity, retraction, hardening or deformation of the penis, or migration of charges was observed. Six months after the injection, the average increase in penis circumference was 1. 91 cm, then the average circumference decreased gradually until 18 months and after a year and a half it was +1. 79 ± 1, 41 cm.
Dynamics of increase in penis circumference after injection of hyaluronic acid filler:
| Study period after administration | Average penis circumference in the group (cm) | Deviation from average value (cm) |
| Before the injection | 7. 74 | ±1. 40 |
| 1 month | 10: 15 a. m. | ±1. 57 |
| 3 months | 10: 25 a. m. | ±1. 64 |
| 6 months | 9. 74 | ±1. 83 |
| 18 months | 9. 08 | ±1. 87 |
Satisfaction level
After a month, the indicators of the appearance of the penis increased significantly. This improvement lasted up to six months. Thereafter, they gradually decreased until 18 months, but the scores at one and a half years were significantly higher than at baseline. After three months, sexual activity rates increased significantly. This increase lasted up to a year and a half.
Study results
The study found that hyaluronic acid led to a significant increase in penis girth and greater satisfaction associated with the injection. The procedure was tolerable and no major complications were observed over 18 months.
Hyaluronic acid is composed of natural ingredients and has a direct and passive effect. After injection, the filler is gradually absorbed by the surrounding tissues. As hyaluronate breaks down into smaller fragments, the molecules bind more water; the same volume can be maintained with less hyaluronic acid for several months. Then the result decreases steadily. The enhancing effect of the filler lasts up to 18 months.

The results of the present study are comparable to the results of previous trials and prove the clinical utility of the gel, its effectiveness and safety. Since hyaluronic fillers are temporary, long-term follow-up after injection is of the utmost importance. As for the augmentative effect, the penis girth after filler injection increased to a maximum in about a month. Satisfaction with penis appearance increased significantly about a month after filler injections. This increase lasted approximately 6 to 12 months. Then they gradually decreased until a year and a half; however, satisfaction levels were even higher than at baseline.
The study demonstrated that increased satisfaction with sexual activity after filler injections lasted for 18 months, despite an increase in penile girth gradually decreasing over time. The finding suggests that injecting the filler could alleviate the psychological stress associated with sexual activity. This also supports the idea that men who want to enlarge their penises experience psychological stress. They often require psychological counseling or psychotherapy.
Compatibility of hyaluronate injection with other types of augmentation
The introduction of hyaluronate into the penis can be combined with other surgical interventions:
- ligamentotomy— surgical intervention to cut the ligament supporting the penis;
- liposuction in the pubic area— extraction of the adipose tissue which hides the penis in obese men;
- lipofilling- increase the circumference of the penis shaft with subcutaneous injections of its own lipids;
- scrotal plastic surgery- removal of the scrotal veil, which hides centimeters of the genital organ;
- circumcision of the foreskin- excision of the dermis around the head;
- denervation of the head- reduction of sensitivity by excision of part of the nerves of the penis.
The decision on the compatibility of certain types of penis correction and the need for such surgical interventions is decided by the doctor separately in each specific case.














































